Recombinant Full Length Human MTNR1A Protein, C-Flag-tagged
Cat.No. : | MTNR1A-1482HFL |
Product Overview : | Recombinant Full Length Human MTNR1A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 39.2 kDa |
AA Sequence : | MQGNGSALPNASQPVLRGDGARPSW LASALACVLIFTIVVDILGNLLVIL SVYRNKKLRNAGNIFVVSLA VADLVVAIYPYPLVLMSIFNNGWNL GYLHCQVSGFLMGLSVIGSIFNITG IAINRYCYICHSLKYDKLYS SKNSLCYVLLIWLLTLAAVLPNLRA GTLQYDPRIYSCTFAQSVSSAYTIA VVVFHFLVPMIIVIFCYLRI WILVLQVRQRVKPDRKPKLKPQDFR NFVTMFVVFVLFAICWAPLNFIGLA VASDPASMVPRIPEWLFVAS YYMAYFNSCLNAIIYGLLNQNFRKE YRRIIVSLCTARVFFVDSSNDVADR VKWKPSPLMTNNNVVKVDSVTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, GPCR, Transmembrane |
Protein Pathways : | Neuroactive ligand-receptor interaction |
Gene Name : | MTNR1A melatonin receptor 1A [ Homo sapiens (human) ] |
Official Symbol : | MTNR1A |
Synonyms : | MT1; MEL-1A-R |
Gene ID : | 4543 |
mRNA Refseq : | NM_005958.4 |
Protein Refseq : | NP_005949.1 |
MIM : | 600665 |
UniProt ID : | P48039 |
Products Types
◆ Recombinant Protein | ||
MTNR1A-1142C | Recombinant Chicken MTNR1A Protein, His-tagged | +Inquiry |
Mtnr1a-4221M | Recombinant Mouse Mtnr1a Protein, Myc/DDK-tagged | +Inquiry |
MTNR1A-5726H | Recombinant Human MTNR1A Protein, GST-tagged | +Inquiry |
MTNR1A-1455H | Recombinant Human MTNR1A Protein, His (Fc)-Avi-tagged | +Inquiry |
MTNR1A-8163G | Recombinant Goat MTNR1A protein, His & S-tagged | +Inquiry |
◆ Lysates | ||
MTNR1A-4071HCL | Recombinant Human MTNR1A 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1430 | MTNR1A CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1431 | cAMP MTNR1A CHO-K1 GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket