Recombinant Full Length Human MYBL2 Protein, C-Flag-tagged

• Cat.No.: MYBL2-1690HFL
• Product Overview: Recombinant Full Length Human MYBL2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 78.6 kDa
• AA Sequence: MSRRTRCEDLDELHYQDTDSDVPEQ RDSKCKVKWTHEEDEQLRALVRQFG QQDWKFLASHFPNRTDQQCQ YRWLRVLNPDLVKGPWTKEEDQKVI ELVKKYGTKQWTLIAKHLKGRLGKQ CRERWHNHLNPEVKKSCWTE EEDRIICEAHKVLGNRWAEIAKMLP GRTDNAVKNHWNSTIKRKVDTGGFL SESKDCKPPVYLLLELEDKD GLQSAQPTEGQGSLLTNWPSVPPTI KEEENSEEELAAATTSKEQEPIGTD LDAVRTPEPLEEFPKREDQE GSPPETSLPYKWVVEAANLLIPAVG SSLSEALDLIESDPDAWCDLSKFDL PEEPSAEDSINNSLVQLQAS HQQQVLPPRQPSALVPSVTEYRLDG HTISDLSRSSRGELIPISPSTEVGG SGIGTPPSVLKRQRKRRVAL SPVTENSTSLSFLDSCNSLTPKSTP VKTLPFSPSQFLNFWNKQDTLELES PSLTSTPVCSQKVVVTTPLH RDKTPLHQKHAAFVTPDQKYSMDNT PHTPTPFKNALEKYGPLKPLPQTPH LEEDLKEVLRSEAGIELIIE DDIRPEKQKRKPGLRRSPIKKVRKS LALDIVDEDVKLMMSTLPKSLSLPT TAPSNSSSLTLSGIKEDNSL LNQGFLQAKPEKAAVAQKPRSHFTT PAPMSSAWKTVACGGTRDQLFMQEK ARQLLGRLKPSHTSRTLILSTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Gene Information

• Gene Name: MYBL2 MYB proto-oncogene like 2 [ Homo sapiens (human) ]
• Official Symbol: MYBL2
• Synonyms: BMYB; B-MYB
• Gene ID: 4605
• mRNA Refseq: NM_002466.4
• Protein Refseq: NP_002457.1
• MIM: 601415
• UniProt ID: P10244