Recombinant Full Length Human MYL2 Protein, C-Flag-tagged

• Cat.No.: MYL2-960HFL
• Product Overview: Recombinant Full Length Human MYL2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a major sarcomeric protein in mammalian striated muscle. The encoded protein plays a role in embryonic heart muscle structure and function, while phosphorylation of the encoded protein is involved in cardiac myosin cycling kinetics, torsion and function in adults. Mutations in this gene are associated with hypertrophic cardiomyopathy 10 and infant-onset myopathy.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 18.6 kDa
• AA Sequence: MAPKKAKKRAGGANSNVFSMFEQTQ IQEFKEAFTIMDQNRDGFIDKNDLR DTFAALGRVNVKNEEIDEMI KEAPGPINFTVFLTMFGEKLKGADP EETILNAFKVFDPEGKGVLKADYVR EMLTTQAERFSKEEVDQMFA
  AFPPDVTGNLDYKNLVHIITHGEEK DTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Cardiac muscle contraction, Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Tight junction

Gene Information

• Gene Name: MYL2 myosin light chain 2 [ Homo sapiens (human) ]
• Official Symbol: MYL2
• Synonyms: MLC2; CMH10; MFM12; MLC-2; MLC-2v; MLC-2s/v
• Gene ID: 4633
• mRNA Refseq: NM_000432.4
• Protein Refseq: NP_000423.2
• MIM: 160781
• UniProt ID: P10916