Recombinant Full Length Human NCF2 Protein

• Cat.No.: NCF2-335HF
• Product Overview: Recombinant full length Human NOXA2/p67phox with N-terminal proprietary tag; 83.86 kDa.

Specification

• Description: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 83.860kDa inclusive of tags
• Protein Length: 526 amino acids
• AA Sequence: MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRIC FNIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGML YYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKID KAMECVWKQKLYEPVVIPVGRLFRPNERQVAQLAKKDYLG KATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATV MFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAP PSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY TVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSN ELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPK ESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLE STRREV
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: NCF2 neutrophil cytosolic factor 2 [ Homo sapiens ]
• Official Symbol: NCF2
• Synonyms: NCF2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil cytosol factor 2; chronic granulomatous disease; autosomal 2; NADPH oxidase activator 2; NOXA2; p67phox
• Gene ID: 4688
• mRNA Refseq: NM_000433
• Protein Refseq: NP_000424
• MIM: 608515
• UniProt ID: P19878