Recombinant Full Length Human NEDD9 Protein, C-Flag-tagged

• Cat.No.: NEDD9-76HFL
• Product Overview: Recombinant Full Length Human NEDD9 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 92.7 kDa
• AA Sequence: MKYKNLMARALYDNVPECAEELAFR KGDILTVIEQNTGGLEGWWLCSLHG RQGIVPGNRVKLLIGPMQET ASSHEQPASGLMQQTFGQQKLYQVP NPQAAPRDTIYQVPPSYQNQGIYQV PTGHGTQEQEVYQVPPSVQR SIGGTSGPHVGKKVITPVRTGHGYV YEYPSRYQKDVYDIPPSHTTQGVYD IPPSSAKGPVFSVPVGEIKP QGVYDIPPTKGVYAIPPSACRDEAG LREKDYDFPPPMRQAGRPDLRPEGV YDIPPTCTKPAGKDLHVKYN CDIPGAAEPVARRHQSLSPNHPPPQ LGQSVGSQNDAYDVPRGVQFLEPPA ETSEKANPQERDGVYDVPLH NPPDAKGSRDLVDGINRLSFSSTGS TRSNMSTSSTSSKESSLSASPAQDK RLFLDPDTAIERLQRLQQAL EMGVSSLMALVTTDWRCYGYMERHI NEIRTAVDKVELFLKEYLHFVKGAV ANAACLPELILHNKMKRELQ RVEDSHQILSQTSHDLNECSWSLNI LAINKPQNKCDDLDRFVMVAKTVPD DAKQLTTTINTNAEALFRPG PGSLHLKNGPESIMNSTEYPHGGSQ GQLLHPGDHKAQAHNKALPPGLSKE QAPDCSSSDGSERSWMDDYD YVHLQGKEEFERQQKELLEKENIMK QNKMQLEHHQLSQFQLLEQEITKPV ENDISKWKPSQSLPTTNSGV SAQDRQLLCFYYDQCETHFISLLNA IDALFSCVSSAQPPRIFVAHSKFVI LSAHKLVFIGDTLTRQVTAQ
  DIRNKVMNSSNQLCEQLKTIVMATK MAALHYPSTTALQEMVHQVTDLSRN AQLFKRSLLEMATFTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: NEDD9 neural precursor cell expressed, developmentally down-regulated 9 [ Homo sapiens (human) ]
• Official Symbol: NEDD9
• Synonyms: CAS2; CASL; HEF1; CAS-L; CASS2
• Gene ID: 4739
• mRNA Refseq: NM_006403.4
• Protein Refseq: NP_006394.1
• MIM: 602265
• UniProt ID: Q14511