Recombinant Full Length Human NPR3 Protein, C-Flag-tagged

• Cat.No.: NPR3-104HFL
• Product Overview: Recombinant Full Length Human NPR3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 59.6 kDa
• AA Sequence: MPSLLVLTFSPCVLLGWALLAGGTG GGGVGGGGGGAGIGGGRQEREALPP QKIEVLVLLPQDDSYLFSLT RVRPAIEYALRSVEGNGTGRRLLPP GTRFQVAYEDSDCGNRALFSLVDRV AAARGAKPDLILGPVCEYAA APVARLASHWDLPMLSAGALAAGFQ HKDSEYSHLTRVAPAYAKMGEMMLA LFRHHHWSRAALVYSDDKLE RNCYFTLEGVHEVFQEEGLHTSIYS FDETKDLDLEDIVRNIQASERVVIM CASSDTIRSIMLVAHRHGMT SGDYAFFNIELFNSSSYGDGSWKRG DKHDFEAKQAYSSLQTVTLLRTVKP EFEKFSMEVKSSVEKQGLNM EDYVNMFVEGFHDAILLYVLALHEV LRAGYSKKDGGKIIQQTWNRTFEGI AGQVSIDANGDRYGDFSVIA MTDVEAGTQEVIGDYFGKEGRFEMR PNVKYPWGPLKLRIDENRIVEHTNS SPCKSCGLEESAVTGIVVGA
  LLGAGLLMAFYFFRKKYRITIERRT QQEESNLGKHRELREDSIRSHFSVA TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: NPR3 natriuretic peptide receptor 3 [ Homo sapiens (human) ]
• Official Symbol: NPR3
• Synonyms: NPRC; ANP-C; ANPRC; BOMOS; NPR-C; ANPR-C; GUCY2B; C5orf23
• Gene ID: 4883
• mRNA Refseq: NM_000908.4
• Protein Refseq: NP_000899.1
• MIM: 108962
• UniProt ID: P17342