Recombinant Full Length Human PDE1A Protein, C-Flag-tagged
Cat.No. : | PDE1A-779HFL |
Product Overview : | Recombinant Full Length Human PDE1A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+). |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 62.1 kDa |
AA Sequence : | MGSSATEIEELENTTFKYLTGEQTE KMWQRLKGILRCLVKQLERGDVNVV DLKKNIEYAASVLEAVYIDE TRRLLDTEDELSDIQTDSVPSEVRD WLASTFTRKMGMTKKKPEEKPKFRS IVHAVQAGIFVERMYRKTYH MVGLAYPAAVIVTLKDVDKWSFDVF ALNEASGEHSLKFMIYELFTRYDLI NRFKIPVSCLITFAEALEVG YSKYKNPYHNLIHAADVTQTVHYIM LHTGIMHWLTELEILAMVFAAAIHD YEHTGTTNNFHIQTRSDVAI LYNDRSVLENHHVSAAYRLMQEEEM NILINLSKDDWRDLRNLVIEMVLST DMSGHFQQIKNIRNSLQQPE GIDRAKTMSLILHAADISHPAKSWK LHYRWTMALMEEFFLQGDKEAELGL PFSPLCDRKSTMVAQSQIGF IDFIVEPTFSLLTDSTEKIVIPLIE EASKAETSSYVASSSTTIVGLHIAD ALRRSNTKGSMSDGSYSPDY SLAAVDLKSFKNNLVDIIQQNKERW KELAAQGESDLHKNSEDLVNAEEKH DETHSTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction |
Gene Name : | PDE1A phosphodiesterase 1A [ Homo sapiens (human) ] |
Official Symbol : | PDE1A |
Synonyms : | HCAM1; HCAM-1; HSPDE1A; CAM-PDE 1A; CAM-PDE-1A |
Gene ID : | 5136 |
mRNA Refseq : | NM_005019.7 |
Protein Refseq : | NP_005010.2 |
MIM : | 171890 |
UniProt ID : | P54750 |
Products Types
◆ Recombinant Protein | ||
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PDE1A-29692TH | Recombinant Human PDE1A | +Inquiry |
◆ Lysates | ||
PDE1A-3353HCL | Recombinant Human PDE1A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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