Recombinant Full Length Human PIEZO1 Protein, GST-tagged

• Cat.No.: PIEZO1-4578HF
• Product Overview: Human FAM38A full-length ORF ( AAH08073, 1 a.a. - 373 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 66.77 kDa
• Protein Length: 373 amino acids
• AA Sequence: MKICPFSSKSSIVLALKFRSLIHFE KYPQPKGQKKKKIVKYGMGGLIILF LIAIIWFPLLFMSLVRSVVGVVNQP IDVTVTLKLGGYEPLFTMSAQQPSI IPFTAQAYEELSRQFDPQPLAMQFI SQYSPEDIVTAQIEGSSGALWRISP PSRAQMKRELYNGTADITLRFTWNF QRDLAKGGTVEYANEKHMLALAPNS TARRQLASLLEGTSDQSVVIPNLFP KYIRAPNGPEANPVKQLQPNEEADY LGVRIQLRREQGAGATGFLEWWVIE LQECRTDCNLLPMVIFSDKHHGAVR VHRAGHRQVRARILQRDLALHYVRG AAVRGPHPQALPGHLPGAGDSGAGA GGGVVCQAHLPLPLTGDHDQVDS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: PIEZO1 piezo type mechanosensitive ion channel component 1 [ Homo sapiens (human) ]
• Official Symbol: PIEZO1
• Synonyms: PIEZO1; piezo type mechanosensitive ion channel component 1; Piezo Type Mechanosensitive Ion Channel Component 1; Piezo-Type Mechanosensitive Ion Channel Component 1; Membrane Protein Induced By Beta-Amyloid Treatment; Family With Sequence Similarity 38, Member A; FAM38A; MIB; Protein FAM38A; KIAA0233; LMPH3; DHS; piezo-type mechanosensitive ion channel component 1; family with sequence similarity 38, member A; membrane protein induced by beta-amyloid treatment
• Gene ID: 9780
• mRNA Refseq: NM_001142864
• Protein Refseq: NP_001136336
• MIM: 611184
• UniProt ID: Q92508