Recombinant Full Length Human POMP Protein, GST-tagged

• Cat.No.: POMP-1771HF
• Product Overview: Human C13orf12 full-length ORF ( NP_057016.1, 1 a.a. - 141 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 42.2 kDa
• Protein Length: 141 amino acids
• AA Sequence: MNARGLGSELKDSIPVTELSASGPF ESHDLLRKGFSCVKNELLPSHPLEL SEKNFQLNQDKMNFSTLRNIQGLFA PLKLQMEFKAVQQVQRLPFLSSSNL SLDVLRGNDETIGFEDILNDPSQSE VMGEPHLMVEYKLGLL
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: POMP proteasome maturation protein [ Homo sapiens ]
• Official Symbol: POMP
• Synonyms: POMP; proteasome maturation protein; C13orf12, chromosome 13 open reading frame 12; HSPC014; proteassemblin; UMP1; hUMP1; 2510048O06Rik; protein UMP1 homolog; voltage-gated K channel beta subunit 4.1; voltage-gated potassium channel beta subunit 4.1; C13orf12; PNAS-110
• Gene ID: 51371
• mRNA Refseq: NM_015932
• Protein Refseq: NP_057016
• MIM: 613386
• UniProt ID: Q9Y244