Recombinant Full Length Human POSTN Protein, C-Flag-tagged

• Cat.No.: POSTN-677HFL
• Product Overview: Recombinant Full Length Human POSTN Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 87.1 kDa
• AA Sequence: MIPFLPMFSLLLLLIVNPINANNHY DKILAHSRIRGRDQGPNVCALQQIL GTKKKYFSTCKNWYKKSICG QKTTVLYECCPGYMRMEGMKGCPAV LPIDHVYGTLGIVGATTTQRYSDAS KLREEIEGKGSFTYFAPSNE AWDNLDSDIRRGLESNVNVELLNAL HSHMINKRMLTKDLKNGMIIPSMYN NLGLFINHYPNGVVTVNCAR IIHGNQIATNGVVHVIDRVLTQIGT SIQDFIEAEDDLSSFRAAAITSDIL EALGRDGHFTLFAPTNEAFE KLPRGVLERIMGDKVASEALMKYHI LNTLQCSESIMGGAVFETLEGNTIE IGCDGDSITVNGIKMVNKKD IVTNNGVIHLIDQVLIPDSAKQVIE LAGKQQTTFTDLVAQLGLASALRPD GEYTLLAPVNNAFSDDTLSM DQRLLKLILQNHILKVKVGLNELYN GQILETIGGKQLRVFVYRTAVCIEN SCMEKGSKQGRNGAIHIFRE IIKPAEKSLHEKLKQDKRFSTFLSL LEAADLKELLTQPGDWTLFVPTNDA FKGMTSEEKEILIRDKNALQ NIILYHLTPGVFIGKGFEPGVTNIL KTTQGSKIFLKEVNDTLLVNELKSK ESDIMTTNGVIHVVDKLLYP ADTPVGNDQLLEILNKLIKYIQIKF VRGSTFKEIPVTVYRPTLTKVKIEG EPEFRLIKEGETITEVIHGE PIIKKYTKIIDGVPVEITEKETREE RIITGPEIKYTRISTGGGETEETLK KLLQEDTPVRKLQANKKVQG
  SRRRLREGRSQTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: POSTN periostin [ Homo sapiens (human) ]
• Official Symbol: POSTN
• Synonyms: PN; OSF2; OSF-2; PDLPOSTN
• Gene ID: 10631
• mRNA Refseq: NM_001135935.2
• Protein Refseq: NP_001129407.1
• MIM: 608777
• UniProt ID: Q15063