Recombinant Full Length Human PXDN Protein, C-Flag-tagged

• Cat.No.: PXDN-280HFL
• Product Overview: Recombinant Full Length Human PXDN Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 165.1 kDa
• AA Sequence: MAKRSRGPGRRCLLALVLFCAWGTL AVVAQKPGAGCPSRCLCFRTTVRCM HLLLEAVPAVAPQTSILDLR FNRIREIQPGAFRRLRNLNTLLLNN NQIKRIPSGAFEDLENLKYLYLYKN EIQSIDRQAFKGLASLEQLY LHFNQIETLDPDSFQHLPKLERLFL HNNRITHLVPGTFNHLESMKRLRLD SNTLHCDCEILWLADLLKTY AESGNAQAAAICEYPRRIQGRSVAT ITPEELNCERPRITSEPQDADVTSG NTVYFTCRAEGNPKPEIIWL RNNNELSMKTDSRLNLLDDGTLMIQ NTQETDQGIYQCMAKNVAGEVKTQE VTLRYFGSPARPTFVIQPQN TEVLVGESVTLECSATGHPPPRISW TRGDRTPLPVDPRVNITPSGGLYIQ NVVQGDSGEYACSATNNIDS VHATAFIIVQALPQFTVTPQDRVVI EGQTVDFQCEAKGNPPPVIAWTKGG SQLSVDRRHLVLSSGTLRIS GVALHDQGQYECQAVNIIGSQKVVA HLTVQPRVTPVFASIPSDTTVEVGA NVQLPCSSQGEPEPAITWNK DGVQVTESGKFHISPEGFLTINDVG PADAGRYECVARNTIGSASVSMVLS VNVPDVSRNGDPFVATSIVE AIATVDRAINSTRTHLFDSRPRSPN DLLALFRYPRDPYTVEQARAGEIFE RTLQLIQEHVQHGLMVDLNG TSYHYNDLVSPQYLNLIANLSGCTA HRRVNNCSDMCFHQKYRTHDGTCNN LQHPMWGASLTAFERLLKSV YENGFNTPRGINPHRLYNGHALPMP RLVSTTLIGTETVTPDEQFTHMLMQ WGQFLDHDLDSTVVALSQAR FSDGQHCSNVCSNDPPCFSVMIPPN DSRARSGARCMFFVRSSPVCGSGMT SLLMNSVYPREQINQLTSYI DASNVYGSTEHEARSIRDLASHRGL LRQGIVQRSGKPLLPFATGPPTECM RDENESPIPCFLAGDHRANE QLGLTSMHTLWFREHNRIATELLKL NPHWDGDTIYYETRKIVGAEIQHIT YQHWLPKILGEVGMRTLGEY HGYDPGINAGIFNAFATAAFRFGHT LVNPLLYRLDENFQPIAQDHLPLHK AFFSPFRIVNEGGIDPLLRG LFGVAGKMRVPSQLLNTELTERLFS MAHTVALDLAAINIQRGRDHGIPPY HDYRVYCNLSAAHTFEDLKN EIKNPEIREKLKRLYGSTLNIDLFP ALVVEDLVPGSRLGPTLMCLLSTQF KRLRDGDRLWYENPGVFSPA QLTQIKQTSLARILCDNADNITRVQ SDVFRVAEFPHGYGSCDEIPRVDLR VWQDCCEDCRTRGQFNAFSY HFRGRRSLEFSYQEDKPTKKTRPRK IPSVGRQGEHLSNSTSAFSTRSDAS GTNDFREFVLEMQKTITDLR TQIKKLESRLSTTECVDAGGESHAN NTKWKKDACTICECKDGQVTCFVEA CPPATCAVPVNIPGACCPVC
  LQKRAEEKPTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: PXDN peroxidasin [ Homo sapiens (human) ]
• Official Symbol: PXDN
• Synonyms: PXN; VPO; MG50; PRG2; ASGD7; COPOA; D2S448; D2S448E; hsPxd01
• Gene ID: 7837
• mRNA Refseq: NM_012293.3
• Protein Refseq: NP_036425.1
• MIM: 605158
• UniProt ID: Q92626