Recombinant Full Length Human RASGRP2 Protein, C-Flag-tagged
Cat.No. : | RASGRP2-662HFL |
Product Overview : | Recombinant Full Length Human RASGRP2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 69.1 kDa |
AA Sequence : | MAGTLDLDKGCTVEELLRGCIEAFD DSGKVRDPQLVRMFLMMHPWYIPSS QLAAKLLHIYQQSRKDNSNS LQVKTCHLVRYWISAFPAEFDLNPE LAEQIKELKALLDQEGNRRHSSLID IDSVPTYKWKRQVTQRNPVG QKKRKMSLLFDHLEPMELAEHLTYL EYRSFCKILFQDYHSFVTHGCTVDN PVLERFISLFNSVSQWVQLM ILSKPTAPQRALVITHFVHVAEKLL QLQNFNTLMAVVGGLSHSSISRLKE THSHVSPETIKLWEGLTELV TATGNYGNYRRRLAACVGFRFPILG VHLKDLVALQLALPDWLDPARTRLN GAKMKQLFSILEELAMVTSL RPPVQANPDLLSLLTVSLDQYQTED ELYQLSLQREPRSKSSPTSPTSCTP PPRPPVLEEWTSAAKPKLDQ ALVVEHIEKMVESVFRNFDVDGDGH ISQEEFQIIRGNFPYLSAFGDLDQN QDGCISREEMVSYFLRSSSV LGGRMGFVHNFQESNSLRPVACRHC KALILGIYKQGLKCRACGVNCHKQC KDRLSVECRRRAQSVSLEGS APSPSPMHSHHHRAFSFSLPRPGRR GSRPPEIREEEVQTVEDGVFDIHLT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Chemokine signaling pathway, MAPK signaling pathway |
Gene Name : | RASGRP2 RAS guanyl releasing protein 2 [ Homo sapiens (human) ] |
Official Symbol : | RASGRP2 |
Synonyms : | CDC25L; CALDAG-GEFI |
Gene ID : | 10235 |
mRNA Refseq : | NM_001098671.2 |
Protein Refseq : | NP_001092141.1 |
MIM : | 605577 |
UniProt ID : | Q7LDG7 |
Products Types
◆ Recombinant Protein | ||
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RASGRP2-3610R | Recombinant Rhesus Macaque RASGRP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RASGRP2-1861H | Recombinant Human RASGRP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RASGRP2-33H | Recombinant Human RASGRP2 protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
RASGRP2-2505HCL | Recombinant Human RASGRP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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