Recombinant Full Length Human S100A11 Protein, C-Flag-tagged
Cat.No. : | S100A11-1178HFL |
Product Overview : | Recombinant Full Length Human S100A11 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 11.6 kDa |
AA Sequence : | MAKISSPTETERCIESLIAVFQKYA GKDGYNYTLSKTEFLSFMNTELAAF TKNQKDPGVLDRMMKKLDTNSDGQL DFSEFLNLIGGLAMACHDSFLKAVP SQKRTTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Gene Name : | S100A11 S100 calcium binding protein A11 [ Homo sapiens (human) ] |
Official Symbol : | S100A11 |
Synonyms : | MLN70; S100C; HEL-S-43 |
Gene ID : | 6282 |
mRNA Refseq : | NM_005620.2 |
Protein Refseq : | NP_005611.1 |
MIM : | 603114 |
UniProt ID : | P31949 |
Products Types
◆ Recombinant Protein | ||
S100A11-4870R | Recombinant Rat S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-1935H | Recombinant Human S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100a11-5665M | Recombinant Mouse S100a11 Protein, Myc/DDK-tagged | +Inquiry |
S100A11-5480H | Recombinant Human S100 Calcium Binding Protein A11, His-tagged | +Inquiry |
S100A11-7865M | Recombinant Mouse S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
S100A11-3111H | Native Human S100A11 protein(Met1-Thr105) | +Inquiry |
◆ Lysates | ||
S100A11-2095HCL | Recombinant Human S100A11 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Q&As (5)
Ask a questionS100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.
S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.
S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.
Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.
S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.
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