Recombinant Full Length Human SERPINH1 Protein, C-Flag-tagged

• Cat.No.: SERPINH1-495HFL
• Product Overview: Recombinant Full Length Human SERPINH1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.5 kDa
• AA Sequence: MRSLLLLSAFCLLEAALAAEVKKPA AAAAPGTAEKLSPKAATLAERSAGL AFSLYQAMAKDQAVENILVS PVVVASSLGLVSLGGKATTASQAKA VLSAEQLRDEEVHAGLGELLRSLSN STARNVTWKLGSRLYGPSSV SFADDFVRSSKQHYNCEHSKINFRD KRSALQSINEWAAQTTDGKLPEVTK DVERTDGALLVNAMFFKPHW DEKFHHKMVDNRGFMVTRSYTVGVM MMHRTGLYNYYDDEKEKLQIVEMPL AHKLSSLIIFMPHHVEPLER LEKLLTKEQLKIWMGKMQKKAVAIS LPKGVVEVTHDLQKHLAGLGLTEAI DKNKADLSRMSGKKDLYLAS VFHATAFELDTDGNPFDQDIYGREE LRSPKLFYADHPFIFLVRDTQSGSL LFIGRLVRPKGDKMRDELTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: SERPINH1 serpin family H member 1 [ Homo sapiens (human) ]
• Official Symbol: SERPINH1
• Synonyms: CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2
• Gene ID: 871
• mRNA Refseq: NM_001235.5
• Protein Refseq: NP_001226.2
• MIM: 600943
• UniProt ID: P50454