Recombinant Full Length Human SH3KBP1 Protein, C-Flag-tagged

• Cat.No.: SH3KBP1-1656HFL
• Product Overview: Recombinant Full Length Human SH3KBP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 72.9 kDa
• AA Sequence: MVEAIVEFDYQAQHDDELTISVGEI ITNIRKEDGGWWEGQINGRRGLFPD NFVREIKKEMKKDPLTNKAP EKPLHEVPSGNSLLSSETILRTNKR GERRRRRCQVAFSYLPQNDDELELK VGDIIEVVGEVEEGWWEGVL NGKTGMFPSNFIKELSGESDELGIS QDEQLSKSSLRETTGSESDGGDSSS TKSEGANGTVATAAIQPKKV KGVGFGDIFKDKPIKLRPRSIEVEN DFLPVEKTIGKKLPATTATPDSSKT EMDSRTKSKDYCKVIFPYEA QNDDELTIKEGDIVTLINKDCIDVG WWEGELNGRRGVFPDNFVKLLPPDF EKEGNRPKKPPPPSAPVIKQ GAGTTERKHEIKKIPPERPEMLPNR TEEKERPEREPKLDLQKPSVPAIPP KKPRPPKTNSLSRPGALPPR RPERPVGPLTHTRGDSPKIDLAGSS LSGILDKDLSDRSNDIDLEGFDSVV SSTEKLSHPTTSRPKATGRR PPSQSLTSSSLSSPDIFDSPSPEED KEEHISLAHRGVDASKKTSKTVTIS QVSDNKASLPPKPGTMAAGG GGPAPLSSAVPSPLSSSLGTAGHRA NSPSLFGTEGKPKMEPAASSQAAVE ELRTQVRELRSIIETMKDQQ
  KREIKQLLSELDEEKKIRLRLQMEV NDIKKALQSKTRRLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis

Gene Information

• Gene Name: SH3KBP1 SH3 domain containing kinase binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: SH3KBP1
• Synonyms: HSB1; AGMX2; CIN85; GIG10; HSB-1; IMD61; MIG18; CD2BP3
• Gene ID: 30011
• mRNA Refseq: NM_031892.3
• Protein Refseq: NP_114098.1
• MIM: 300374
• UniProt ID: Q96B97