Recombinant Full Length Human SNCA Protein, C-Flag-tagged
Cat.No. : | SNCA-326HFL |
Product Overview : | Recombinant Full Length Human SNCA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 14.3 kDa |
AA Sequence : | MDVFMKGLSKAKEGVVAAAEKTKQG VAEAAGKTKEGVLYVGSKTKEGVVH GVATVAEKTKEQVTNVGGAV VTGVTAVAQKTVEGAGSIAAATGFV KKDQLGKNEEGAPQEGILEDMPVDP DNEAYEMPSEEGYQDYEPEA TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Alzheimer's disease, Parkinson's disease |
Gene Name : | SNCA synuclein alpha [ Homo sapiens (human) ] |
Official Symbol : | SNCA |
Synonyms : | PD1; NACP; PARK1; PARK4 |
Gene ID : | 6622 |
mRNA Refseq : | NM_000345.4 |
Protein Refseq : | NP_000336.1 |
MIM : | 163890 |
UniProt ID : | P37840 |
Products Types
◆ Recombinant Protein | ||
SNCA-5297R | Recombinant Rat SNCA Protein, His (Fc)-Avi-tagged | +Inquiry |
SNCA-2744H | Recombinant Human SNCA protein(11-110 aa), C-His-tagged | +Inquiry |
SNCA-2058H | Recombinant Human SNCA Protein, MYC/DDK-tagged | +Inquiry |
SNCA-8524M | Recombinant Mouse SNCA Protein, His (Fc)-Avi-tagged | +Inquiry |
SNCA-01H | Active Recombinant Human SNCA Protein | +Inquiry |
◆ Native Protein | ||
SNCA-27342TH | Native Human SNCA | +Inquiry |
SNCA-27341TH | Native Human SNCA | +Inquiry |
SNCA-27339TH | Native Human SNCA | +Inquiry |
◆ Lysates | ||
SNCA-1634HCL | Recombinant Human SNCA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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