Recombinant Full Length Human SOD2 Protein, C-Flag-tagged

• Cat.No.: SOD2-1397HFL
• Product Overview: Recombinant Full Length Human SOD2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 22.2 kDa
• AA Sequence: MLSRAVCGTSRQLAPVLGYLGSRQK HSLPDLPYDYGALEPHINAQIMQLH HSKHHAAYVNNLNVTEEKYQ EALAKGDVTAQIALQPALKFNGGGH INHSIFWTNLSPNGGGEPKGELLEA IKRDFGSFDKFKEKLTAASV GVQGSGWGWLGFNKERGHLQIAACP NQDPLQGTTGLIPLLGIDVWEHAYY LQYKNVRPDYLKAIWNVINW
  ENVTERYMACKKTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Huntington's disease

Gene Information

• Gene Name: SOD2 superoxide dismutase 2 [ Homo sapiens (human) ]
• Official Symbol: SOD2
• Synonyms: GC1; IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD
• Gene ID: 6648
• mRNA Refseq: NM_000636.4
• Protein Refseq: NP_000627.2
• MIM: 147460
• UniProt ID: P04179