Recombinant Full Length Human SPTLC1 Protein, C-Flag-tagged
Cat.No. : | SPTLC1-1155HFL |
Product Overview : | Recombinant Full Length Human SPTLC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 52.6 kDa |
AA Sequence : | MATATEQWVLVEMVQALYEAPAYHL ILEGILILWIIRLLFSKTYKLQERS DLTVKEKEELIEEWQPEPLV PPVPKDHPALNYNIVSGPPSHKTVV NGKECINFASFNFLGLLDNPRVKAA ALASLKKYGVGTCGPRGFYG TFDVHLDLEDRLAKFMKTEEAIIYS YGFATIASAIPAYSKRGDIVFVDRA ACFAIQKGLQASRSDIKLFK HNDMADLERLLKEQEIEDQKNPRKA RVTRRFIVVEGLYMNTGTICPLPEL VKLKYKYKARIFLEESLSFG VLGEHGRGVTEHYGINIDDIDLISA NMENALASIGGFCCGRSFVIDHQRL SGQGYCFSASLPPLLAAAAI EALNIMEENPGIFAVLKEKCGQIHK ALQGISGLKVVGESLSPAFHLQLEE STGSREQDVRLLQEIVDQCM NRSIALTQARYLEKEEKCLPPPSIR VVVTVEQTEEELERAASTIKEVAQA VLLTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Transmembrane |
Protein Pathways : | Metabolic pathways, Sphingolipid metabolism |
Gene Name : | SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Homo sapiens (human) ] |
Official Symbol : | SPTLC1 |
Synonyms : | HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1 |
Gene ID : | 10558 |
mRNA Refseq : | NM_006415.4 |
Protein Refseq : | NP_006406.1 |
MIM : | 605712 |
UniProt ID : | O15269 |
Products Types
◆ Recombinant Protein | ||
SPTLC1-2092H | Recombinant Human SPTLC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Sptlc1-02M | Recombinant Mouse Sptlc1 Protein, Myc/DDK-tagged | +Inquiry |
Sptlc1-680M | Recombinant Mouse Sptlc1 Protein, His-tagged | +Inquiry |
SPTLC1-01H | Recombinant Human SPTLC1 Protein, Myc/DDK-tagged | +Inquiry |
Sptlc1-6117M | Recombinant Mouse Sptlc1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
SPTLC1-1485HCL | Recombinant Human SPTLC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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