Recombinant Full Length Human SSX4 Protein, C-Flag-tagged

• Cat.No.: SSX4-1341HFL
• Product Overview: Recombinant Full Length Human SSX4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 21.7 kDa
• AA Sequence: MNGDDAFARRPRDDAQISEKLRKAF DDIAKYFSKKEWEKMKSSEKIVYVY MKLNYEVMTKLGFKVTLPPF MRSKRAADFHGNDFGNDRNHRNQVE RPQMTFGSLQRIFPKIMPKKPAEEE NGLKEVPEASGPQNDGKQLC
  PPGNPSTLEKINKTSGPKRGKHAWT HRLRERKQLVVYEEISDPEEDDETR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors

Gene Information

• Gene Name: SSX4 SSX family member 4 [ Homo sapiens (human) ]
• Official Symbol: SSX4
• Synonyms: CT5.4
• Gene ID: 6759
• mRNA Refseq: NM_005636.4
• Protein Refseq: NP_005627.1
• MIM: 300326
• UniProt ID: O60224