Recombinant Full Length Human STAR Protein

• Cat.No.: STAR-504HF
• Product Overview: Recombinant full length Human StAR with N terminal proprietary tag, 57.46kDa inclusive of tag. Purified from an in vitro wheat germ expression system.

Specification

• Description: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 57.460kDa inclusive of tags
• Protein Length: 286 amino acids
• AA Sequence: MLLATFKLCAGSSYRHMRNMKGLRQQAVMAISQELNRRAL GGPTPSTWINQVRRRSSLLGSRLEETLYSDQELAYLQQGE EAMQKALGILSNQEGWKKESQQDNGDKVMSKVVPDVGKVF RLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKI GKDTFITHELAAEAAGNLVGPRDFVSVRCAKRRGSTCVLA GMATDFGNMPEQKGVIRAEHGPTCMVLHPLAGSPSKTKLT WLLSIDLKGWLPKSIINQVLSQTQVDFANHLRKRLESHPA SEARC
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: STAR steroidogenic acute regulatory protein [ Homo sapiens ]
• Official Symbol: STAR
• Synonyms: STAR; steroidogenic acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein, mitochondrial; StAR; StAR related lipid transfer (START) domain containing 1; STARD1
• Gene ID: 6770
• mRNA Refseq: NM_000349
• Protein Refseq: NP_000340
• MIM: 600617
• UniProt ID: P49675