Recombinant Full Length Human STK25 Protein, C-Flag-tagged

• Cat.No.: STK25-2112HFL
• Product Overview: Recombinant Full Length Human STK25 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.9 kDa
• AA Sequence: MAHLRGFANQHSRVDPEELFTKLDR IGKGSFGEVYKGIDNHTKEVVAIKI IDLEEAEDEIEDIQQEITVL SQCDSPYITRYFGSYLKSTKLWIIM EYLGGGSALDLLKPGPLEETYIATI LREILKGLDYLHSERKIHRD IKAANVLLSEQGDVKLADFGVAGQL TDTQIKRNTFVGTPFWMAPEVIKQS AYDFKADIWSLGITAIELAK GEPPNSDLHPMRVLFLIPKNSPPTL EGQHSKPFKEFVEACLNKDPRFRPT AKELLKHKFITRYTKKTSFL TELIDRYKRWKSEGHGEESSSEDSD IDGEAEDGEQGPIWTFPPTIRPSPH SKLHKGTALHSSQKPAEPVK RQPRSQCLSTLVRPVFGELKEKHKQ SGGSVGALEELENAFSLAEESCPGI SDKLMVHLVERVQRFSHNRN HLTSTR TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protein Kinase

Gene Information

• Gene Name: STK25 serine/threonine kinase 25 [ Homo sapiens (human) ]
• Official Symbol: STK25
• Synonyms: SOK1; YSK1
• Gene ID: 10494
• mRNA Refseq: NM_006374.5
• Protein Refseq: NP_006365.2
• MIM: 602255
• UniProt ID: O00506