Recombinant Full Length Human TAPBPL Protein, C-Flag-tagged

• Cat.No.: TAPBPL-842HFL
• Product Overview: Recombinant Full Length Human TAPBPL Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 50 kDa
• AA Sequence: MGTQEGWCLLLCLALSGAAETKPHP AEGQWRAVDVVLDCFLVKDGAHRGA LASSEDRARASLVLKQVPVL DDGSLEDFTDFQGGTLAQDDPPIIF EASVDLVQIPQAEALLHADCSGKEV TCEISRYFLQMTETTVKTAA WFMANVQVSGGGPSISLVMKTPRVA KNEVLWHPTLNLPLSPQGTVRTAVE FQVMTQTQSLSFLLGSSASL DCGFSMAPGLDLISVEWRLQHKGRG QLVYSWTAGQGQAVRKGATLEPAQL GMARDASLTLPGLTIQDEGT YICQITTSLYRAQQIIQLNIQASPK VRLSLANEALLPTLICDIAGYYPLD VVVTWTREELGGSPAQVSGA SFSSLRQSVAGTYSISSSLTAEPGS AGATYTCQVTHISLEEPLGASTQVV PPERRTALGVIFASSLFLLA
  LMFLGLQRRQAPTGLGLLQAERWET TSCADTQSSHLHEDRTARVSQPSTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: TAPBPL TAP binding protein like [ Homo sapiens (human) ]
• Official Symbol: TAPBPL
• Synonyms: TAPBPR; TAPBP-R
• Gene ID: 55080
• mRNA Refseq: NM_018009.5
• Protein Refseq: NP_060479.3
• MIM: 607081
• UniProt ID: Q9BX59