Recombinant Full Length Human TNFRSF14 Protein, C-Flag-tagged

• Cat.No.: TNFRSF14-928HFL
• Product Overview: Recombinant Full Length Human TNFRSF14 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 26.1 kDa
• AA Sequence: MEPPGDWGPPPWRSTPRTDVLRLVL YLTFLGAPCYAPALPSCKEDEYPVG SECCPKCSPGYRVKEACGEL TGTVCEPCPPGTYIAHLNGLSKCLQ CQMCDPAMGLRASRNCSRTENAVCG CSPGHFCIVQDGDHCAACRA YATSSPGQRVQKGGTESQDTLCQNC PPGTFSPNGTLEECQHQTKCSWLVT KAGAGTSSSHWVWWFLSGSL VIVIVCSTVGLIICVKRRKPRGDVV KVIVSVQRKRQEAEGEATVIEALQA PPDVTTVAVEETIPSFTGRS
  PNHTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction

Gene Information

• Gene Name: TNFRSF14 TNF receptor superfamily member 14 [ Homo sapiens (human) ]
• Official Symbol: TNFRSF14
• Synonyms: TR2; ATAR; HVEA; HVEM; CD270; LIGHTR
• Gene ID: 8764
• mRNA Refseq: NM_003820.4
• Protein Refseq: NP_003811.2
• MIM: 602746
• UniProt ID: Q92956