Recombinant Full Length Human TNFSF4 Protein, C-Flag-tagged

• Cat.No.: TNFSF4-1935HFL
• Product Overview: Recombinant Full Length Human TNFSF4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 20.9 kDa
• AA Sequence: MERVQPLEENVGNAARPRFERNKLL LVASVIQGLGLLLCFTYICLHFSAL QVSHRYPRIQSIKVQFTEYK KEKGFILTSQKEDEIMKVQNNSVII NCDGFYLISLKGYFSQEVNISLHYQ KDEEPLFQLKKVRSVNSLMV ASLTYKDKVYLNVTTDNTSLDDFHV NGGELILIHQNPGEFCVL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction

Gene Information

• Gene Name: TNFSF4 TNF superfamily member 4 [ Homo sapiens (human) ]
• Official Symbol: TNFSF4
• Synonyms: GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; TNLG2B
• Gene ID: 7292
• mRNA Refseq: NM_003326.5
• Protein Refseq: NP_003317.1
• MIM: 603594
• UniProt ID: P23510