Recombinant Full Length Human TOLLIP Protein, C-Flag-tagged

• Cat.No.: TOLLIP-1594HFL
• Product Overview: Recombinant Full Length Human TOLLIP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 30.1 kDa
• AA Sequence: MATTVSTQRGPVYIGELPQDFLRIT PTQQQRQVQLDAQAAQQLQYGGAVG TVGRLNITVVQAKLAKNYGM TRMDPYCRLRLGYAVYETPTAHNGA KNPRWNKVIHCTVPPGVDSFYLEIF DERAFSMDDRIAWTHITIPE SLRQGKVEDKWYSLSGRQGDDKEGM INLVMSYALLPAAMVMPPQPVVLMP TVYQQGVGYVPITGMPAVCS
  PGMVPVALPPAAVNAQPRCSEEDLK AIQDMFPNMDQEVIRSVLEAQRGNK DAAINSLLQMGEEPTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Toll-like receptor signaling pathway

Gene Information

• Gene Name: TOLLIP toll interacting protein [ Homo sapiens (human) ]
• Official Symbol: TOLLIP
• Synonyms: IL-1RAcPIP
• Gene ID: 54472
• mRNA Refseq: NM_019009.4
• Protein Refseq: NP_061882.2
• MIM: 606277
• UniProt ID: Q9H0E2