Recombinant Full Length Human UBE3C Protein, C-Flag-tagged

• Cat.No.: UBE3C-1868HFL
• Product Overview: Recombinant Full Length Human UBE3C Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables ubiquitin protein ligase activity. Involved in protein polyubiquitination. Predicted to be located in nucleus. Predicted to be part of proteasome complex.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 123.7 kDa
• AA Sequence: MFSFEGDFKTRPKVSLGGASRKEEK ASLLHRTQEERRKREEERRRLKNAI IIQSFIRGYRDRKQQYSIQR SAFDRCATLSQSGGAFPIANGPNLT LLVRQLLFFYKQNEDSKRLIWLYQN LIKHSSLFVKQLDGSERLTC LFQIKRLMSLCCRLLQNCNDDSLNV ALPMRMLEVFSSENTYLPVLQDASY VVSVIEQILHYMIHNGYYRS LYLLINSKLPSSIEYSDLSRVPIAK ILLENVLKPLHFTYNSCPEGARQQV FTAFTEEFLAAPFTDQIFHF IIPALADAQTVFPYEPFLNALLLIE SRCSRKSGGAPWLFYFVLTVGENYL GALSEEGLLVYLRVLQTFLS QLPVSPASASCHDSASDSEEESEEA DKPSSPEDGRLSVSYITEECLKKLD TKQQTNTLLNLVWRDSASEE VFTTMASVCHTLMVQHRMMVPKVRL LYSLAFNARFLRHLWFLISSMSTRM ITGSMVPLLQVISRGSPMSF EDSSRIIPLFYLFSSLFSHSLISIH DNEFFGDPIEVVGQRQSSMMPFTLE ELIMLSRCLRDACLGIIKLA YPETKPEVREEYITAFQSIGVTTSS EMQQCIQMEQKRWIQLFKVITNLVK MLKSRDTRRNFCPPNHWLSE QEDIKADKVTQLYVPASRHVWRFRR MGRIGPLQSTLDVGLESPPLSVSEE RQLAVLTELPFVVPFEERVK IFQRLIYADKQEVQGDGPFLDGINV TIRRNYIYEDAYDKLSPENEPDLKK RIRVHLLNAHGLDEAGIDGG GIFREFLNELLKSGFNPNQGFFKTT NEGLLYPNPAAQMLVGDSFARHYYF LGRMLGKALYENMLVELPFA GFFLSKLLGTSADVDIHHLASLDPE VYKNLLFLKSYEDDVEELGLNFTVV NNDLGEAQVVELKFGGKDIP VTSANRIAYIHLVADYRLNRQIRQH CLAFRQGLANVVSLEWLRMFDQQEI QVLISGAQVPISLEDLKSFT NYSGGYSADHPVIKVFWRVVEGFTD EEKRKLLKFVTSCSRPPLLGFKELY PAFCIHNGGSDLERLPTAST CMNLLKLPEFYDETLLRSKLLYAIE CAAGFELS TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis

Gene Information

• Gene Name: UBE3C ubiquitin protein ligase E3C [ Homo sapiens (human) ]
• Official Symbol: UBE3C
• Synonyms: RAUL; HECTH2
• Gene ID: 9690
• mRNA Refseq: NM_014671.3
• Protein Refseq: NP_055486.2
• MIM: 614454
• UniProt ID: Q15386