Recombinant Full Length Human USP3 Protein, C-Flag-tagged

• Cat.No.: USP3-550HFL
• Product Overview: Recombinant Full Length Human USP3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables histone binding activity and thiol-dependent deubiquitinase. Involved in several processes, including DNA repair; histone deubiquitination; and regulation of protein stability. Located in several cellular components, including Flemming body; cytoplasmic ribonucleoprotein granule; and nucleoplasm.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 58.7 kDa
• AA Sequence: MECPHLSSSVCIAPDSAKFPNGSPS SWCCSVCRSNKSPWVCLTCSSVHCG RYVNGHAKKHYEDAQVPLTN HKKSEKQDKVQHTVCMDCSSYSTYC YRCDDFVVNDTKLGLVQKVREHLQN LENSAFTADRHKKRKLLENS TLNSKLLKVNGSTTAICATGLRNLG NTCFMNAILQSLSNIEQFCCYFKEL PAVELRNGKTAGRRTYHTRS QGDNNVSLVEEFRKTLCALWQGSQT AFSPESLFYVVWKIMPNFRGYQQQD AHEFMRYLLDHLHLELQGGF NGVSRSAILQENSTLSASNKCCING ASTVVTAIFGGILQNEVNCLICGTE SRKFDPFLDLSLDIPSQFRS KRSKNQENGPVCSLRDCLRSFTDLE ELDETELYMCHKCKKKQKSTKKFWI QKLPKVLCLHLKRFHWTAYL RNKVDTYVEFPLRGLDMKCYLLEPE NSGPESCLYDLAAVVVHHGSGVGSG HYTAYATHEGRWFHFNDSTV
  TLTDEETVVKAKAYILFYVEHQAKA GSDKLTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease

Gene Information

• Gene Name: USP3 ubiquitin specific peptidase 3 [ Homo sapiens (human) ]
• Official Symbol: USP3
• Synonyms: UBP; SIH003
• Gene ID: 9960
• mRNA Refseq: NM_006537.4
• Protein Refseq: NP_006528.2
• MIM: 604728
• UniProt ID: Q9Y6I4