Recombinant Full Length Human VCAM1 Protein, C-Flag-tagged

• Cat.No.: VCAM1-1473HFL
• Product Overview: Recombinant Full Length Human VCAM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 78.7 kDa
• AA Sequence: MPGKMVVILGASNILWIMFAASQAF KIETTPESRYLAQIGDSVSLTCSTT GCESPFFSWRTQIDSPLNGK VTNEGTTSTLTMNPVSFGNEHSYLC TATCESRKLEKGIQVEIYSFPKDPE IHLSGPLEAGKPITVKCSVA DVYPFDRLEIDLLKGDHLMKSQEFL EDADRKSLETKSLEVTFTPVIEDIG KVLVCRAKLHIDEMDSVPTV RQAVKELQVYISPKNTVISVNPSTK LQEGGSVTMTCSSEGLPAPEIFWSK KLDNGNLQHLSGNATLTLIA MRMEDSGIYVCEGVNLIGKNRKEVE LIVQEKPFTVEISPGPRIAAQIGDS VMLTCSVMGCESPSFSWRTQ IDSPLSGKVRSEGTNSTLTLSPVSF ENEHSYLCTVTCGHKKLEKGIQVEL YSFPRDPEIEMSGGLVNGSS VTVSCKVPSVYPLDRLEIELLKGET ILENIEFLEDTDMKSLENKSLEMTF IPTIEDTGKALVCQAKLHID DMEFEPKQRQSTQTLYVNVAPRDTT VLVSPSSILEEGSSVNMTCLSQGFP APKILWSRQLPNGELQPLSE NATLTLISTKMEDSGVYLCEGINQA GRSRKEVELIIQVTPKDIKLTAFPS ESVKEGDTVIISCTCGNVPE TWIILKKKAETGDTVLKSIDGAYTI RKAQLKDAGVYECESKNKVGSQLRS LTLDVQGRENNKDYFSPELL
  VLYFASSLIIPAIGMIIYFARKANM KGSYSLVEAQKSKVTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Gene Information

• Gene Name: VCAM1 vascular cell adhesion molecule 1 [ Homo sapiens (human) ]
• Official Symbol: VCAM1
• Synonyms: CD106; INCAM-100
• Gene ID: 7412
• mRNA Refseq: NM_001078.4
• Protein Refseq: NP_001069.1
• MIM: 192225
• UniProt ID: P19320