Recombinant Full Length Human VCAM1 Protein, C-Flag-tagged

Cat.No. : VCAM1-1473HFL
Product Overview : Recombinant Full Length Human VCAM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
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Description : This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 78.7 kDa
AA Sequence : MPGKMVVILGASNILWIMFAASQAF KIETTPESRYLAQIGDSVSLTCSTT GCESPFFSWRTQIDSPLNGK VTNEGTTSTLTMNPVSFGNEHSYLC TATCESRKLEKGIQVEIYSFPKDPE IHLSGPLEAGKPITVKCSVA DVYPFDRLEIDLLKGDHLMKSQEFL EDADRKSLETKSLEVTFTPVIEDIG KVLVCRAKLHIDEMDSVPTV RQAVKELQVYISPKNTVISVNPSTK LQEGGSVTMTCSSEGLPAPEIFWSK KLDNGNLQHLSGNATLTLIA MRMEDSGIYVCEGVNLIGKNRKEVE LIVQEKPFTVEISPGPRIAAQIGDS VMLTCSVMGCESPSFSWRTQ IDSPLSGKVRSEGTNSTLTLSPVSF ENEHSYLCTVTCGHKKLEKGIQVEL YSFPRDPEIEMSGGLVNGSS VTVSCKVPSVYPLDRLEIELLKGET ILENIEFLEDTDMKSLENKSLEMTF IPTIEDTGKALVCQAKLHID DMEFEPKQRQSTQTLYVNVAPRDTT VLVSPSSILEEGSSVNMTCLSQGFP APKILWSRQLPNGELQPLSE NATLTLISTKMEDSGVYLCEGINQA GRSRKEVELIIQVTPKDIKLTAFPS ESVKEGDTVIISCTCGNVPE TWIILKKKAETGDTVLKSIDGAYTI RKAQLKDAGVYECESKNKVGSQLRS LTLDVQGRENNKDYFSPELL
VLYFASSLIIPAIGMIIYFARKANM KGSYSLVEAQKSKVTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families : Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways : Cell adhesion molecules (CAMs), Leukocyte transendothelial migration
FACS: Coomassie blue staining of purified VCAM1 protein.
Gene Name : VCAM1 vascular cell adhesion molecule 1 [ Homo sapiens (human) ]
Official Symbol : VCAM1
Synonyms : CD106; INCAM-100
Gene ID : 7412
mRNA Refseq : NM_001078.4
Protein Refseq : NP_001069.1
MIM : 192225
UniProt ID : P19320

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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