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Recombinant Human VCAM1, His-tagged

Cat.No. : VCAM1-31199TH
Product Overview : Recombinant fragment corresponding to amino acids 109-331 of Human VCAM1 with an amino-terminal hexahistidine tag; 203 amino acids, 25kDa.
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Description : This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Conjugation : HIS
Source : E. coli
Tissue specificity : Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 1x Laemmli Buffer (2.5% Glycerol, 1% SDS, 0.1% Bromophenol blue, 50mM DTT, 25mM Tris HCl, pH 6.8)
Storage : Store at -20°C. Stable for 12 months at -20°C
Sequence Similarities : Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Gene Name : VCAM1 vascular cell adhesion molecule 1 [ Homo sapiens ]
Official Symbol : VCAM1
Synonyms : VCAM1; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; CD106;
Gene ID : 7412
mRNA Refseq : NM_001078
Protein Refseq : NP_001069
MIM : 192225
Uniprot ID : P19320
Chromosome Location : 1p32-p31
Pathway : Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;
Function : cell adhesion molecule binding; cell adhesion molecule binding; integrin binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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