Recombinant Full Length Human WDR83 Protein, C-Flag-tagged

• Cat.No.: WDR83-1629HFL
• Product Overview: Recombinant Full Length Human WDR83 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 34.2 kDa
• AA Sequence: MAFPEPKPRPPELPQKRLKTLDCGQ GAVRAVRFNVDGNYCLTCGSDKTLK LWNPLRGTLLRTYSGHGYEV LDAAGSFDNSSLCSGGGDKAVVLWD VASGQVVRKFRGHAGKVNTVQFNEE ATVILSGSIDSSIRCWDCRS RRPEPVQTLDEARDGVSSVKVSDHE ILAGSVDGRVRRYDLRMGQLFSDYV GSPITCTCFSRDGQCTLVSS LDSTLRLLDKDTGELLGEYKGHKNQ EYKLDCCLSERDTHVVSCSEDGKVF FWDLVEGALALALPVGSGVV
  QSLAYHPTEPCLLTAMGGSVQCWRE EAYEAEDGAGTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: WDR83 WD repeat domain 83 [ Homo sapiens (human) ]
• Official Symbol: WDR83
• Synonyms: MORG1
• Gene ID: 84292
• mRNA Refseq: NM_032332.4
• Protein Refseq: NP_115708.1
• MIM: 616850
• UniProt ID: Q9BRX9