Recombinant Horse MMP9 protein

• Cat.No.: MMP9-6754H
• Product Overview: Recombinant Horse MMP9 protein(F7AGL5)(20-640aa) was expressed in Yeast.

Specification

• Source: Yeast
• Species: Horse
• Tag: Non
• Protein length: 20-640aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 69.0 kDa
• AASequence: APTRHQPTVVVFPGDLLTNLTDREL AEEYLFRYGYTGVAEMSEGDQPLER ALRRLQKRLALPETGELDSTTLEAM RTPRCGVPDVGQFQTFEGDLKWHHR DITYWIQNYSGDLPRDVIDDAFARA FAVWSEVTPLTFTRVNGPQADIVIQ FGVREHGDGYPFDGKDGLLAHAFPP GPGIQGDAHFDDEELWSLGKGPVVP THFGNADGAPCHFPFTFEGRSYSSC TTDGRSDDMLWCSTTADYDTDRRFG FCPSEKLYTQDGNADGKPCVFPFTF EGRSYSTCTTDGRSDGYRWCATTAN YDQDKRYGFCPTRVDSTVNGGNSAG ELCVFPFTFLGKEYSACTREGRSDG RLWCATTSNFDSDKKWGFCPDQGYS LFLVAAHEFGHALGLDHSSVPAALM YPMYSFTEEPPLHEDDVNGIQYLYG PRPKPEPQPPTTTTLEPQTTVCATG PPTTRPSERPTAGPTGPPSAGPTGP PSAGPPTNPPTAGPSTAPTVPLGPG EEVCNVDIFDAIAEIGNHLHFFKDG RYWRLLEGKGRGVQGPFLIRDTWPM LPPKLDSAFEEPLTKKIFFFSGRQV WVYTGKSALGPRRLDKLGLGADVAQ ITGALPRGGGKVLLFSRRRFW
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) [ Equus caballus ]
• Official Symbol: MMP9
• Synonyms: MMP9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase-9; matrix metalloproteinase 9
• Gene ID: 100056599
• mRNA Refseq: NM_001111302
• Protein Refseq: NP_001104772

Reviews

05/03/2020

The superior quality of this recombined protein has significantly enhanced the precision of our research outcomes.

08/15/2019

Fast shipping! Ordered this product, and it arrived well-packaged and ready for use in our experiments.

01/21/2018

Customer service went above and beyond to accommodate our specific needs, ensuring a smooth purchasing experience.

Q&As

What are the consequences of dysregulated MMP9 expression in cancer progression?

Dysregulated MMP9 expression is associated with cancer invasion and metastasis, as it enables tumor cells to degrade the extracellular matrix and invade surrounding tissues.

What is the impact of MMP9 polymorphisms on enzyme activity?

Polymorphisms in the MMP9 gene can influence enzyme activity, potentially affecting the individual's susceptibility to certain diseases and the progression of pathological conditions.

Can you explain the role of MMP9 in tissue remodeling at the molecular level?

MMP9 facilitates tissue remodeling by cleaving structural proteins in the extracellular matrix, such as collagen and gelatin, leading to changes in tissue architecture.

What is the role of MMP9 in the breakdown of the blood-brain barrier during neurological disorders?

MMP9 contributes to the breakdown of the blood-brain barrier by degrading tight junction proteins, potentially exacerbating neurological disorders and neuroinflammation.

How does MMP9 contribute to angiogenesis at the molecular level?

MMP9 plays a role in angiogenesis by promoting the release and activation of growth factors sequestered in the extracellular matrix, facilitating the formation of new blood vessels.