Recombinant Human AADC Protein, His-tagged
Cat.No. : | AADC-01H |
Product Overview : | Recombinant Human AADC Protein with His tag was expressed in E. coli. |
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Description : | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 48.64 kDa |
AA Sequence : | MNASEFRRRGKEMVDYVANYMEGIE GRQVYPDVEPGYLRPLIPAAAPQEP DTFEDIINDVEKIIMPGVTHWHSPY FFAYFPTASSYPAMLADMLCGAIGC IGFSWAASPACTELETVMMDWLGKM LELPKAFLNEKAGEGGGVIQGSASE ATLVALLAARTKVIHRLQAASPELT QAAIMEKLVAYSSDQMVATLGTTTC CSFDNLLEVGPICNKEDIWLHVDAA YAGSAFICPEFRHLLNGVEFADSFN FNPHKWLLVNFDCSAMWVKKRTDLT GAFRLDPTYLKHSHQDSGLITDYRH WQIPLGRRFRSLKMWFVFRMYGVKG LQAYIRKHVQLSHEFESLVRQDPRF EICVEVILGLVCFRLKGSNKVNEAL LQRINSAKKIHLVPCHLRDKFVLRF AICSRTVESAHVQRAWEHIKHHHHH HHH |
Purity : | > 85% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.5 mg/mL |
Storage Buffer : | PBS, pH 7.4 |
Gene Name : | DDC dopa decarboxylase [ Homo sapiens (human) ] |
Official Symbol : | DDC |
Synonyms : | DDC; dopa decarboxylase; AADC; aromatic-L-amino-acid decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); EC 4.1.1.28 |
Gene ID : | 1644 |
mRNA Refseq : | NM_000790 |
Protein Refseq : | NP_000781 |
MIM : | 107930 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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