Recombinant Human ABCB1 Protein, DDK-tagged
Cat.No. : | ABCB1-235H |
Product Overview : | Recombinant human ABCB1 protein, fused to DDK-tag at C-terminal, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008]. |
Source : | Insect cells |
Species : | Human |
Tag : | DDK |
Form : | 50 mM Tris.HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Molecular Mass : | 31.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ATP binding cassette subfamily B member 1 [ Homo sapiens ] |
Official Symbol : | ABCB1 |
Synonyms : | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 |
Gene ID : | 5243 |
mRNA Refseq : | NM_000927.4 |
Protein Refseq : | NP_000918.2 |
MIM : | 171050 |
UniProt ID : | P08183 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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