Recombinant Human ABCB10 Protein (A152-A738), Flag-10×His tagged

• Cat.No.: ABCB10-0241H
• Product Overview: Recombinant Human ABCB10(A152-A738 end)-TEV-Flag-10His Protein was expressed in Mammalian cell.

Specification

• Description: Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria.
• Source: Mammalian cell
• Species: Human
• Tag: Flag-10His
• Form: Liquid
• Protein Length: A152-A738
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 95%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM HEPES (pH 7.5), 150 mM NaCl, 0.02% GDN, 0.0002% CHS
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 [ Homo sapiens (human) ]
• Official Symbol: ABCB10
• Synonyms: ABCB10; ATP-binding cassette, sub-family B (MDR/TAP), member 10; ATP-binding cassette sub-family B member 10, mitochondrial; ABC transporter 10 protein; ATP binding cassette sub family B member 10; mitochondrial; ATP binding cassette transporter 10; EST20237; M ABC2; mitochondrial ATP binding cassette 2; MTABC2; ATP-binding cassette transporter 10; mitochondrial ATP-binding cassette 2; M-ABC2
• Gene ID: 23456
• mRNA Refseq: NM_012089
• Protein Refseq: NP_036221
• MIM: 605454
• UniProt ID: Q9NRK6