Recombinant Human ABCB5, His-tagged

• Cat.No.: ABCB5-9209H
• Product Overview: Recombinant human ABCB5 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 583-702a.a.
• Description: ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 [ Homo sapiens ]
• Official Symbol: ABCB5
• Synonyms: ABCB5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; ATP-binding cassette sub-family B member 5; ABCB5alpha; ABCB5beta; ATP binding cassette protein; EST422562; P glycoprotein ABCB5; ABCB5 P-gp; P-glycoprotein ABCB5; ATP-binding cassette protein
• Gene ID: 340273
• mRNA Refseq: NM_001163941
• Protein Refseq: NP_001157413
• MIM: 611785
• UniProt ID: Q2M3G0
• Chromosome Location: 7p14
• Pathway: ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
• Function: ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; efflux transmembrane transporter activity; nucleotide binding