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Recombinant Human ABCD1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : ABCD1-5658H
Product Overview : ABCD1 MS Standard C13 and N15-labeled recombinant protein (NP_000024) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 82.9 kDa
AA Sequence : MPVLSRPRPWRGNTLKRTAVLLALA AYGAHKVYPLVRQCLAPARGLQAPA GEPTQEASGVAAAKAGMNRVFLQRL LWLLRLLFPRVLCRETGLLALHSAA LVSRTFLSVYVARLDGRLARCIVRK DPRAFGWQLLQWLLIALPATFVNSA IRYLEGQLALSFRSRLVAHAYRLYF SQQTYYRVSNMDGRLRNPDQSLTED VVAFAASVAHLYSNLTKPLLDVAVT SYTLLRAARSRGAGTAWPSAIAGLV VFLTANVLRAFSPKFGELVAEEARR KGELRYMHSRVVANSEEIAFYGGHE VELALLQRSYQDLASQINLILLERL WYVMLEQFLMKYVWSASGLLMVAVP IITATGYSESDAEAVKKAALEKKEE ELVSERTEAFTIARNLLTAAADAIE RIMSSYKEVTELAGYTARVHEMFQV FEDVQRCHFKRPRELEDAQAGSGTI GRSGVRVEGPLKIRGQVVDVEQGII CENIPIVTPSGEVVVASLNIRVEEG MHLLITGPNGCGKSSLFRILGGLWP TYGGVLYKPPPQRMFYIPQRPYMSV GSLRDQVIYPDSVEDMQRKGYSEQD LEAILDVVHLHHILQREGGWEAMCD WKDVLSGGEKQRIGMARMFYHRPKY ALLDECTSAVSIDVEGKIFQAAKDA GIALLSITHRPSLWKYHTHLLQFDG EGGWKFEKLDSAARLSLTEEKQRLE QQLAGIPKMQRRLQELCQILGEAVA PAHVPAPSPQGPGGLQGASTTRTRP LEQKLISEEDLAANDILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : ABCD1 ATP binding cassette subfamily D member 1 [ Homo sapiens (human) ]
Official Symbol : ABCD1
Synonyms : ABCD1; ATP-binding cassette, sub-family D (ALD), member 1; ALD; ATP-binding cassette sub-family D member 1; adrenoleukodystrophy; ALDP; AMN; adrenoleukodystrophy protein; ABC42;
Gene ID : 215
mRNA Refseq : NM_000033
Protein Refseq : NP_000024
MIM : 300371
UniProt ID : P33897

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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