Recombinant Human ABCE1, His-tagged

• Cat.No.: ABCE1-3740H
• Product Overview: ATP-binding cassette sub-family E member 1 (ABCE1)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 599
• Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of ABCE1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 [ Homo sapiens ]
• Official Symbol: ABCE1
• Synonyms: RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI
• Gene ID: 6059
• mRNA Refseq: NM_002940.2
• Protein Refseq: NP_002931.2
• MIM: 601213
• UniProt ID: P61221
• Chromosome Location: 4q31
• Function: ATP binding;ATPase activity;electron carrier activity;iron-sulfur cluster binding;ribonuclease inhibitor activity