Recombinant Human ABCG2 Protein, GST-Tagged
Cat.No. : | ABCG2-066H |
Product Overview : | Human ABCG2 partial ORF ( NP_004818, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 37.84 kDa |
AA Sequence : | MSSSNVEVFIPVSQGNTNGFPATVS NDLKAFTEGAVLSFHNICYRVKLKS GFLPCRKPVEKEILSNINGIMKPGL NAILGPTGGGKSSLLDVLAARKDPS GLSGDVLING |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 [ Homo sapiens ] |
Official Symbol : | ABCG2 |
Synonyms : | ABCG2; ATP-binding cassette, sub-family G (WHITE), member 2; ATP-binding cassette sub-family G member 2; ABCP; BCRP; CD338; EST157481; MXR; ABC transporter; placenta specific MDR protein; breast cancer resistance protein; ATP-binding cassette transporter G2; mitoxantrone resistance-associated protein; placenta-specific ATP-binding cassette transporter; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; MRX; BMDP; MXR1; ABC15; BCRP1; GOUT1; CDw338; UAQTL1; MGC102821; |
Gene ID : | 9429 |
mRNA Refseq : | NM_001257386 |
Protein Refseq : | NP_001244315 |
MIM : | 603756 |
UniProt ID : | Q9UNQ0 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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