Recombinant Human ABO Protein (Arg63-Pro354), HIgG1 Fc-tagged

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Recombinant Human ABO Protein (Arg63-Pro354), HIgG1 Fc-tagged

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Cat.No. : ABO-605H
Product Overview : Recombinant Human ABO Protein (ADX99264.1) (Arg63-Pro354) was produced by HEK293 Cells expression system. This protein was expressed with the Fc region of human IgG1 at the N-terminus.
Description : ABO (ABO, Alpha 1-3-N-Acetylgalactosaminyltransferase And Alpha 1-3-Galactosyltransferase) is a Protein Coding gene. Homologous glycosyltransferases α-(1→3)-N-acetylgalactosaminyltransferase (GTA) and α-(1→3)-galactosyltransferase (GTB) catalyze the final step in ABO(H) blood group A and B antigen synthesis through sugar transfer from activated donor to the H antigen acceptor. These enzymes have a GT-A fold type with characteristic mobile polypeptide loops that cover the active site upon substrate binding. The homologous glycosyltransferases α-1,3-N-acetylgalactosaminyltransferase (GTA) and α-1,3-galactosyltransferase (GTB) carry out the final synthetic step of the closely related human ABO(H) blood group A and B antigens.
Source : HEK293
Species : Human
Tag : HIgG1 Fc
Predicted N Terminal : Glu
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human ABO consists 552 amino acids and predicts a molecular mass of 62.4 kDa.
Protein length : Arg63-Pro354
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > (73.8+20.7) % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) [ Homo sapiens ]
Official Symbol : ABO
Synonyms : ABO; A3GALNT; A3GALT1; ABO glycosyltransferase; GTB; NAGAT;
Gene ID : 28
mRNA Refseq : NM_020469
Protein Refseq : NP_065202
UniProt ID : P16442

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