Recombinant Human ACADS Protein, GST-Tagged

• Cat.No.: ACADS-135H
• Product Overview: Human ACADS full-length ORF ( AAH25963.1, 1 a.a. - 412 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms. [provided by RefSeq, Oct 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 95.4 kDa
• AA Sequence: MSGCGLFLRTTAAARACRGLVVSTA NRRLLRTSPPVRAFAKELFLGKIKK KEVFPFPEVSQDELNEINQFLGPVE KFFTEEVDSRKIDQEGKIPDETLEK LKSLGLFGLQVPEEYGGLGFSNTMY SRLGEIISMDGSITVTLAAHQAIGL KGIILAGTEEQKAKYLPKLASGEHI AAFCLTEPASGSDAASIRSRATLSE DKKHYILNGSKVWITNGGLANIFTV FAKTEVVDSDGSVKDKITAFIVERD FGGVTNGKPEDKLGIRGSNTCEVHF ENTKIPVENILGEVGDGFKVAMNIL NSGRFSMGSVVAGLLKRLIEMTAEY ACTRKQFNKRLSEFGLIQEKFALMA QKAYVMESMTYLTAGMLDQPGFPDC SIEAAMVKVFSSEAAWQCVSEALQI LGGLGYTRDYPYERILRDTRILLIF EGTNEILRMYIALTGLQHAGRILTT RIHELKQAKVSTVMDTVGRRLRDSL GRTVDLGLTGNHGVVHPSLADSANK FEENTYCFGRTVETLLLRFGKTIME EQLVLKRVANILINLYGMTAVLSRA SRSIRIGLRNHDHEVLLANTFCVEA YLQNLFSLSQLDKYAPENLDEQIKK VSQQILEKRAYICAHPLDRTC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain [ Homo sapiens ]
• Official Symbol: ACADS
• Synonyms: ACADS; acyl-CoA dehydrogenase, C-2 to C-3 short chain; acyl Coenzyme A dehydrogenase, C 2 to C 3 short chain; short-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD3; SCAD; butyryl-CoA dehydrogenase; unsaturated acyl-CoA reductase; short-chain acyl-CoA dehydrogenase; acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain; mitochondrial short-chain specific acyl-CoA dehydrogenase
• Gene ID: 35
• mRNA Refseq: NM_000017
• Protein Refseq: NP_000008
• MIM: 606885
• UniProt ID: P16219