Recombinant Human ACE2 Protein, His-tagged

• Cat.No.: ACE2-735H
• Product Overview: Recombinant protein of human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) with a C-His tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Description: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
• Molecular Mass: 84.6 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test.
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 20mM Tris-HCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5.

Gene Information

• Gene Name: ACE2 angiotensin I converting enzyme 2 [ Homo sapiens (human) ]
• Official Symbol: ACE2
• Synonyms: ACE2; angiotensin I converting enzyme 2; ACEH; angiotensin-converting enzyme 2; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme homolog; metalloprotease MPROT15; peptidyl-dipeptidase A; EC 3.4.17.23
• Gene ID: 59272
• mRNA Refseq: NM_021804
• Protein Refseq: NP_068576
• MIM: 300335
• UniProt ID: Q9BYF1