Recombinant Human ACKR2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human ACKR2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : ACKR2-1629H
Product Overview : CCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001287) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 43.4 kDa
AA Sequence : MAATASPQPL ATEDADSENS SFYYYDYLDE VAFMLCRKDA VVSFGKVFLP VFYSLIFVLG LSGNLLLLMV LLRYVPRRRM VEIYLLNLAI SNLLFLVTLP FWGISVAWHW VFGSFLCKMV STLYTINFYS GIFFISCMSL DKYLEIVHAQ PYHRLRTRAK SLLLATIVWA VSLAVSIPDM VFVQTHENPK GVWNCHADFG GHGTIWKLFL RFQQNLLGFL LPLLAMIFFY SRIGCVLVRL RPAGQGRALK IAAALVVAFF VLWFPYNLTL FLHTLLDLQV FGNCEVSQHL DYALQVTESI AFLHCCFSPI LYAFSSHRFR QYLKAFLAAV LGWHLAPGTA QASLSSCSES SILTAQEEMT GMNDLGERQS ENYPNKEDVG NKSATRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : ACKR2 atypical chemokine receptor 2 [ Homo sapiens (human) ]
Official Symbol : ACKR2
Synonyms : ACKR2; atypical chemokine receptor 2; D6; hD6; CCR9; CCBP2; CCR10; CMKBR9; atypical chemokine receptor 2; C-C chemokine receptor D6; CC-chemokine-binding receptor JAB61; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine receptor CCR-10; chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; chemokine-binding protein D6
Gene ID : 1238
mRNA Refseq : NM_001296
Protein Refseq : NP_001287
MIM : 602648
UniProt ID : O00590

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