Recombinant Human ACLY Protein (4-265 aa), His-SUMO-tagged

• Cat.No.: ACLY-1907H
• Product Overview: Recombinant Human ACLY Protein (4-265 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial.

Specification

• Description: ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 45.5 kDa
• Protein length: 4-265 aa
• AA Sequence: KAISEQTGKELLYKFICTTSAIQNR FKYARVTPDTDWARLLQDHPWLLSQ NLVVKPDQLIKRRGKLGLVGVNLTL DGVKSWLKPRLGQEATVGKATGFLK NFLIEPFVPHSQAEEFYVCIYATRE GDYVLFHHEGGVDVGDVDAKAQKLL VGVDEKLNPEDIKKHLLVHAPEDKK EILASFISGLFNFYEDLYFTYLEIN PLVVTKDGVYVLDLAAKVDATADYI CKVKWGDIEFPPPFGREAYPEEAYI ADLDAKSGASLK
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: ACLY ATP citrate lyase [ Homo sapiens ]
• Official Symbol: ACLY
• Synonyms: ACLY; ATP citrate lyase; ATP-citrate synthase; ACL; ATPCL; CLATP
• Gene ID: 47
• mRNA Refseq: NM_001096
• Protein Refseq: NP_001087
• MIM: 108728
• UniProt ID: P53396