Recombinant Human ACOT11, GST-tagged

• Cat.No.: ACOT11-9296H
• Product Overview: Recombinant Human ACOT11 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-221a.a.
• Description: This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ACOT11 acyl-CoA thioesterase 11 [ Homo sapiens ]
• Official Symbol: ACOT11
• Synonyms: ACOT11; acyl-CoA thioesterase 11; THEA, thioesterase, adipose associated; acyl-coenzyme A thioesterase 11; BFIT; BFIT1; KIAA0707; StAR related lipid transfer (START) domain containing 14; STARD14; THEM1; START domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase, adipose associated; thioesterase superfamily member 1; StAR-related lipid transfer (START) domain containing 14; THEA; DKFZp667O1916
• Gene ID: 26027
• mRNA Refseq: NM_015547
• Protein Refseq: NP_056362
• MIM: 606803
• UniProt ID: Q8WXI4
• Chromosome Location: 1p32.3
• Function: acyl-CoA hydrolase activity; carboxylesterase activity; hydrolase activity