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Recombinant Human ACOT11, GST-tagged

Cat.No. : ACOT11-9296H
Product Overview : Recombinant Human ACOT11 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-221a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : ACOT11 acyl-CoA thioesterase 11 [ Homo sapiens ]
Official Symbol : ACOT11
Synonyms : ACOT11; acyl-CoA thioesterase 11; THEA, thioesterase, adipose associated; acyl-coenzyme A thioesterase 11; BFIT; BFIT1; KIAA0707; StAR related lipid transfer (START) domain containing 14; STARD14; THEM1; START domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase, adipose associated; thioesterase superfamily member 1; StAR-related lipid transfer (START) domain containing 14; THEA; DKFZp667O1916;
Gene ID : 26027
mRNA Refseq : NM_015547
Protein Refseq : NP_056362
MIM : 606803
UniProt ID : Q8WXI4
Chromosome Location : 1p32.3
Function : acyl-CoA hydrolase activity; carboxylesterase activity; hydrolase activity;

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