Recombinant Human ACTN1 protein, His-tagged
Cat.No. : | ACTN1-45H |
Product Overview : | Recombinant human ACTN1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | ACTN1 also known as alpha-actinin-1 isoform a. ACTN1 functions as an actin-binding-protein. ACTN1 determines the motility of keratinocytes by regulating the organization of the actin cytoskeleton, focal adhesion, and hemidesmosome proteins complexes, thereby modulating cell speed, lamellipodial dynamics, and directed migration. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol |
Molecular Mass : | 31.4kDa (274aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSEFMDHYD SQQTNDYMQP EEDWDRDLLL DPAWEKQQRK TFTAWCNSHL RKAGTQIENI EEDFRDGLKLMLLLEVISGE RLAKPERGKM RVHKISNVNK ALDFIASKGV KLVSIGAEEI VDGNVKMTLG MIWTIILRFA IQDISVEETS AKEGLLLWCQRKTAPYKNVN IQNFHISWKD GLGFCALIHR HRPELIDYGK LRKDDPLTNL NTAFDVAEKY LDIPKMLDAE DIVGTARPDE KAIMTYVSSFYHAF |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Absorbance at 280nm) |
Gene Name : | ACTN1 actinin, alpha 1 [ Homo sapiens ] |
Official Symbol : | ACTN1 |
Synonyms : | ACTN1; actinin, alpha 1; alpha-actinin-1; actinin 1 smooth muscle; non-muscle alpha-actinin-1; F-actin cross-linking protein; alpha-actinin cytoskeletal isoform; FLJ40884; FLJ54432; |
Gene ID : | 87 |
mRNA Refseq : | NM_001102 |
Protein Refseq : | NP_001093 |
MIM : | 102575 |
UniProt ID : | P12814 |
Chromosome Location : | 14q24.1 |
Pathway : | Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell junction organization, organism-specific biosystem; |
Function : | actin binding; actin filament binding; calcium ion binding; integrin binding; ion channel binding; protein binding; protein domain specific binding; vinculin binding; |
Products Types
◆ Recombinant Protein | ||
Actn1-432M | Recombinant Mouse Actn1 Protein, MYC/DDK-tagged | +Inquiry |
ACTN1-435H | Recombinant Human ACTN1 Protein, His-tagged | +Inquiry |
ACTN1-270H | Recombinant Human ACTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTN1-142R | Recombinant Rat ACTN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTN1-486R | Recombinant Rat ACTN1 Protein | +Inquiry |
◆ Native Protein | ||
ACTN1-162C | Native chicken ACTN1 | +Inquiry |
◆ Lysates | ||
ACTN1-9056HCL | Recombinant Human ACTN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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