Recombinant Human ACTR1B Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: ACTR1B-371H
• Product Overview: ACTR1B MS Standard C13 and N15-labeled recombinant protein (NP_005726) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 42.3 kDa
• AA Sequence: MESYDIIANQPVVIDNGSGVIKAGF AGDQIPKYCFPNYVGRPKHMRVMAG ALEGDLFIGPKAEEHRGLLTIRYPM EHGVVRDWNDMERIWQYVYSKDQLQ TFSEEHPVLLTEAPLNPSKNREKAA EVFFETFNVPALFISMQAVLSLYAT GRTTGVVLDSGDGVTHAVPIYEGFA MPHSIMRVDIAGRDVSRYLRLLLRK EGVDFHTSAEFEVVRTIKERACYLS INPQKDEALETEKVQYTLPDGSTLD VGPARFRAPELLFQPDLVGDESEGL HEVVAFAIHKSDMDLRRTLFANIVL SGGSTLFKGFGDRLLSEVKKLAPKD IKIKISAPQERLYSTWIGGSILASL DTFKKMWVSKKEYEEDGSRAIHRKT FTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) [ Homo sapiens (human) ]
• Official Symbol: ACTR1B
• Synonyms: ACTR1B; ARP1 actin-related protein 1 homolog B, centractin beta (yeast); ARP1 (actin related protein 1, yeast) homolog B (centractin beta), CTRN2; beta-centractin; centractin beta; actin-related protein 1B; PC3; ARP1B; CTRN2
• Gene ID: 10120
• mRNA Refseq: NM_005735
• Protein Refseq: NP_005726
• MIM: 605144
• UniProt ID: P42025