Recombinant Human ACVR2A Protein, GST-tag

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Recombinant Human ACVR2A Protein, GST-tag

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Cat.No. : ACVR2A-510H
Product Overview : This recombinant fusion protein consists of full-length activin A receptor kinase and a glutathione S-transferase (GST) tag was expressed in Baculovirus. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase.
• Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay
• Expressed in insect cells
• GST tagged for use with Eu-labeled GST antibody
Description : This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Source : Insect Cell
Species : Human
Tag : GST
Form : Frozen
Molecular Mass : 85.3 kDa
Storage : Store at -80 centigrade. At first use, aliquot and store at -80 centigrade to avoid multiple freeze-thaws.
Storage Buffer : 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol.
Shipping : Dry Ice
Gene Name : ACVR2A activin A receptor type 2A [ Homo sapiens (human) ]
Official Symbol : ACVR2A
Synonyms : ACVR2A; activin A receptor type 2A; ACVR2; ACTRII; activin receptor type-2A; activin A receptor, type IIA; EC 2.7.11.30
Gene ID : 92
mRNA Refseq : NM_001616
Protein Refseq : NP_001607
MIM : 102581
UniProt ID : P27037
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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