Active Recombinant Human ACVR2A Protein, GST-tagged
Cat.No. : | ACVR2A-254H |
Product Overview : | Human ACVR2A (NP_001607.1, 162 a.a. - 513 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013] |
Source : | Insect Cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Bio-activity : | The activity was determined by ELISA. The enzyme was incubated with biotinylated substrate protein, and after stopping kinase reaction by EDTA, the reaction solution was transferred into streptavidin- coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG. Substrate: ALK4 inactive mutant. ATP: 100 uM. |
Molecular Mass : | 67 kDa |
Purity : | 95 % by SDS-PAGE/CBB staining |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol) |
Gene Name : | ACVR2A activin A receptor, type IIA [ Homo sapiens ] |
Official Symbol : | ACVR2A |
Synonyms : | ACVR2A; activin A receptor, type IIA; activin A receptor, type II , ACVR2; activin receptor type-2A; ACTRII; ACVR2; |
Gene ID : | 92 |
mRNA Refseq : | NM_001616 |
Protein Refseq : | NP_001607 |
MIM : | 102581 |
UniProt ID : | P27037 |
Products Types
◆ Recombinant Protein | ||
ACVR2A-150R | Recombinant Rat ACVR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR2A-0786H | Recombinant Human ACVR2A Protein (P191-N487), His tagged | +Inquiry |
ACVR2A-290B | Recombinant Bovine ACVR2A Protein, His-tagged | +Inquiry |
ACVR2A-14H | Recombinant Human ACVR2A Protein, Fc tagged | +Inquiry |
ACVR2A-510H | Recombinant Human ACVR2A Protein, GST-tag | +Inquiry |
◆ Lysates | ||
ACVR2A-2280MCL | Recombinant Mouse ACVR2A cell lysate | +Inquiry |
ACVR2A-3096HCL | Recombinant Human ACVR2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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