Recombinant Human ADA Protein (Lys11-Val280)
Cat.No. : | ADA-0689H |
Product Overview : | Recombinant Human ADA Protein (Lys11-Val280) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Adenosine Deaminase (ADA, adenosine aminohydrolase) is one of the key enzymes of purine nucleotide catabolism. It catalyses the hydrolytic deamination of adenosine and deoxy‑adenosine to inosine and deoxyinosine (1, 2). ADA is expressed in virtually all tissues and is expressed at high levels in T-lymphocytes. Adenosine Deaminase deficiency can cause a form of SCID (severe combined immunodeficiency) and lymphopenia in both B- and T-cell lineages (3, 4). ADA can be used as a sensitive diagnostic marker for tuberculous pleuritis (5). Although it is primarily a cytosolic enzyme, ADA is known to be a positive regulator of T-cell co‑activation due to its binding to CD26 at the cell surface. The interaction of ADA with CD26 regulates lymphocyte-epithelial cell adhesion (6) |
Source : | E. coli |
Species : | Human |
Tag : | Tag Free |
Predicted N Terminal : | Inconclusive result, Met predicted. Protein identity confirmed by MS analysis of tryptic fragments. |
Molecular Mass : | 42 kDa |
Protein Length : | Lys11-Val280 |
Purity : | >95% |
Gene Name : | ADA adenosine deaminase [ Homo sapiens (human) ] |
Official Symbol : | ADA |
Synonyms : | ADA; adenosine deaminase; ADA1; adenosine deaminase; adenosine aminohydrolase; EC 3.5.4.4 |
Gene ID : | 100 |
mRNA Refseq : | NM_000022 |
Protein Refseq : | NP_000013 |
MIM : | 608958 |
UniProt ID : | P00813 |
Products Types
◆ Recombinant Protein | ||
ADA-303M | Recombinant Mouse ADA Protein, His (Fc)-Avi-tagged | +Inquiry |
ADA-155R | Recombinant Rat ADA Protein, His (Fc)-Avi-tagged | +Inquiry |
ADA-40H | Recombinant Human ADA Protein, 1-363aa, N-His tagged | +Inquiry |
ADA-756Z | Recombinant Zebrafish ADA | +Inquiry |
ADA-1435C | Recombinant Chicken ADA | +Inquiry |
◆ Native Protein | ||
ADA-P036B | Native Bovine adenosine deaminase therapeutic protein (Pegademase bovine) | +Inquiry |
◆ Lysates | ||
ADA-001HCL | Recombinant Human ADA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1101 | Adenosine Deaminase Activity Assay Kit (Colorimetric) | +Inquiry |
Kit-2148 | Adenosine Deaminase Fluorometric Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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