Recombinant Human ADAR Mutant (K744R) Protein, Myc/DDK-tagged

• Cat.No.: ADAR-127H
• Product Overview: Purified mutant recombinant protein of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 4, mutation at(K744R) with a Myc/DDK tag was expressed in HEK293

Specification

• Description: This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 103.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: > 50 μg/mL as determined by microplate Bradford method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: ADAR adenosine deaminase RNA specific [ Homo sapiens (human) ]
• Official Symbol: ADAR
• Synonyms: ADAR; adenosine deaminase RNA specific; DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP; double-stranded RNA-specific adenosine deaminase; 136 kDa double-stranded RNA-binding protein; adenosine deaminase acting on RNA 1-A; dsRNA adenosine deaminase; dsRNA adeonosine deaminase; interferon-induced protein 4; interferon-inducible protein 4; EC 3.5.4.37
• Gene ID: 103
• mRNA Refseq: NM_001025107
• Protein Refseq: NP_001020278
• MIM: 146920
• UniProt ID: P55265